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                                                              Palm Beach Integrative Medicine

                                                              Detoxification

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                                                              Detoxification is a process in which harmful toxins and waste are released from the body. Toxins are eliminated through the bowel, kidneys, lungs and skin. Once this natural process starts to slow down, the body becomes overwhelmed and overloaded with toxins. When this happens, your body may respond with mild signs such as fatigue, memory loss, skin problems and lowered immunity. When the body becomes severely overloaded with toxins, it can lead to cancer, disease and even death.

                                                              Toxicity is a Major Problem
                                                              Did you know that in the year 2001 alone, more than 6 billion pounds of chemical pollutants were released into the environment? Over the course of a lifetime, we will be exposed to thousands of foreign compounds that can enter our bodies through the food we eat, the air we breathe and directly through our skin. To make matters worse, many of us have substituted healthy meals with a poor diet that significantly lacks nutritional value to fuel the body’s detoxifying capacity. All of these factors can contribute to an accumulation of toxins, or toxicity.

                                                              Where Do Toxins Come From?
                                                              Toxins can come from chemical pollutants, heavy metals, pesticides, drugs, alcohol, active/passive cigarette smoking and food additives. However, toxins can also come from normal metabolism and intestinal build-up of unhealthy bacteria within your own body. 
                                                              • More than 4 million distinct chemical compounds have been formulated over the last half decade.
                                                              • At least one quarter million new chemical formulations are produced every year.
                                                              • More than 400 chemicals have been found in human tissues and fluids-- many of these are known carcinogens.
                                                              • On average, 500 different chemicals can be found in American homes.
                                                              • More than 3,000 chemicals can be legally added to our foods.
                                                              • Our drinking water contains more than 700 chemicals.
                                                              • In the cosmetic and perfume industries alone, more than 800 neurotoxic compounds have been used. 

                                                              How Toxicity Can Affect Your Health

                                                              A number of symptoms and conditions have been associated with possible toxic exposures and toxicity, including:

                                                              • Migraine headache
                                                              • Fibromyalgia
                                                              • Generalized arthralgias (pain in joints)
                                                              • Chemical sensitivity
                                                              • Chronic Fatigue Syndrome

                                                              You Can Reduce Your Risk for Toxicity

                                                              Here are some practical suggestions to help lower your exposure to toxins.

                                                              To minimize toxins in the diet:
                                                              • Avoid foods high in fat, additives and preservatives
                                                              • Eat organically grown vegetabels, fruits and grains
                                                              • Drink plenty of water

                                                              To minimize toxins in the environment:
                                                              • Use an effective air purification system
                                                              • Wear protective clothing and/or apparatus when working with toxic materials
                                                              • Replace furnace and air conditioning filters regularly

                                                              Your Body Can Remove Toxins
                                                              The term detoxification refers to our body’s natural ability to transfer and eliminate toxins. The illustration below outlines the body’s natural detoxification steps and helps us understand how to best strengthen and support this protective mechanism.

                                                              Detoxification of Stored Toxins Involves 3 Stages
                                                              Only substances that are easily dissolved in water, or water-soluble, can be effectively excreted from the body. Toxic compounds, however, are typically stored as fatty molecules and, therefore, do not mix well in water. The detoxification process transforms these toxic, fat-soluble substances into harmless, water-soluble molecules which can then be excreted out of the body.

                                                              Detoxification systems in the body can be summarized in 3 phases:

                                                              Liver Function Phase I:
                                                              Fat-soluble toxins are transformed into intermediate compounds which can be more reactive, but bind more easily to
                                                              non-toxic, water-soluble molecules in Phase II.

                                                              Liver Function Phase II:
                                                              -Formation between the reactive intermediates and water-soluble molecules make the entire compound harmless and ready for excretion out of the body.
                                                              -Without enough supportive Phase II substances, the reactive intermediates can attack healthy tissues and may cause damage.

                                                              Excretion:
                                                              Neutralized toxins, now made water-soluble, are removed from the body in urine via the kidneys or in bile/feces through the intestines.

                                                              Prolonged Fasting May Do More Harm Than Good
                                                              Because the detoxification process needs a lot of energy, fasting with water or juice has been shown to be both ineffective and even dangerous. In fact, prolonged fasting may weaken muscles and other organs, eliminating the essential nutrients required for healthy detoxification rather than eliminating toxins.

                                                              There is Nutritional Support for Detoxification
                                                              Studies have shown that the overall detoxification process is heavily nutrient-dependent, as key steps are fueled by vitamins, minerals and other major food components.

                                                              These are a few nutrients that may help maintain and improve detoxification:
                                                              • Zinc, pantothenic acid and beneficial probiotics
                                                              • Vitamins A, B3, B6, B12, C, E, beta-carotene and folates
                                                              • Amino Acids L-cysteine, L-glutamine and taurine
                                                              • N-acetylcysteine, sodium sulfate and L-glutathione
                                                              • Green tea catechins
                                                              • Low-allergy-potential protein/carbohydrates

                                                              Healthy Detoxification Requires Healthy Nutrients

                                                              Without optimal detoxification, your body will not efficiently remove harmful toxins. Your kidneys play a major role during the final step of detoxification by excreting transformed toxic compounds in urine. An alkaline pH level may be an important consideration for proper kidney function. Therefore, a focused, high-impact, low-allergy-potential nutritional support program to promote an alkaline pH level and improve detoxification capacity may be helpful. 

                                                              From 2006 Advanced Nutrition Publications, Inc.

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